Are You Still High?
THC Metabolites in Urine
contributed by Hamilton |
By Adam L. Moore
In humans, cytochrome P450 contains three primary enzymes involved in the metabolism of Δ9-tetrahydrocannabinol (CYP2C9, CYP2C19, CYP3A4). These enzymes are mostly found in the liver, but can occur in other lipophilic tissues like brain, small intestine, heart, and lungs. THC elimination in the body is dictated by the accumulation of the compound in both adipose tissue and plasma and, due to the lipophilicity of THC, the determination of the concentration through excretion is difficult (1,2). Likewise, states have passed regulations allowing for the legal use of both medicinal and recreational cannabis while workplaces in those states continue to dictate safety regulations with a zero tolerance drug policy culminating in a urine test to determine compliance.
Read the full article now
Log in or register to read this article in full and gain access to The Cannabis Scientist’s entire content archive. It’s FREE!
Or register now - it’s free!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Cannabis Scientist magazine