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Research & Development Medical research

Sink or Swim

How did you investigate this?

We initially used a rapid urine screening test to measure 11-nor-9-carboxy-ΔTHC (THCCOOH; the primary metabolite of cannabis) and then verified the results using an enzyme immunoassay. Measurements for THC and other cannabinoids were performed using ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) and by enzyme immunoassay (EIA). Our findings indicate that cannabis use (in humans) and THC exposure (in rats) are associated with changes in DNA methylation, meaning changes in the way genes are being regulated.

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About the Author

Joanna Cummings

A former library manager and storyteller, I have wanted to write for magazines since I was six years old, when I used to make my own out of foolscap paper and sellotape and distribute them to my family. Since getting my MSc in Publishing, I’ve worked as a freelance writer and content creator for both digital and print, writing on subjects such as fashion, food, tourism, photography – and the history of Roman toilets. Now I can be found working on The Analytical Scientist, finding the ‘human angle’ to cutting-edge science stories.

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